Omega-3 Fatty Acid Supplementation Reduces Intervertebral Disc Degeneration

By Dr. David Graber

A study this week demonstrated that omega-3 fatty acid (n-3 FA) supplementation reduced Intervertebral disc (IVD) degeneration in rats. Rats fed a daily dose n-3 FA diet eicosapentaenoic acid (EPA) and docosahexaenoic acid (DHA) in a 2:1 ratio for two months had reduced IVD degeneration in the lumbar disc. This was measured by a decrease of the arachandonic acid/EPA ratio in the blood, and micro-MRI and histological analysis showing reduced histological signs of IVD degeneration. The authors concluded that n-3 FA dietary supplementation might have potential protective effects on the progression of spinal disc degeneration.

Read more here.

Zachary NaPier, Linda E.A. Kanim, Yasaman Arabi, Khosrowdad Salehi, Barry Sears, Mary Perry, Sang Kim, Dmitriy Sheyn, Hyun W. Bae, Juliane D. Glaeser
(Orthopaedic Stem Cell Research Laboratory, Cedars-Sinai Medical Center, Los Angeles, CA, USA)
Med Sci Monit 2019; 25:9531-9537


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